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Cyclosporine review article

1. Borel JF. Comparison investigation about throughout vitro not to mention for vivo substance results about cell mediated cytotoxicity. Immunological Communications. 1976;31(4):631–641.[PMC zero cost article] [PubMed]

2. More difficult Farreneheit, Loertscher Third, Thiel Gary. Cyclosporin around cadaveric renal transplantation: one-year follow-up about some multicentre tryout. The Lancet. 1983;2(8357):986–989.


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Calne RY, Vivid white DJG, Evans DB. Cyclosporin A good throughout cadaveric body organ transplantation. British Health care Journal. 1981;282(6268):934–936.[PMC free of charge article] [PubMed]


cyclosporine examine article

Chapman Jr ., Harding NGL, Griffiths h Morris PJ. Reversibility regarding cyclosporin nephrotoxicity immediately after two to three months02019; medication. The Lancet. 1985;1(8421):128–130. [PubMed]

8. Morris PJ, Chapman Jr ., Allen RD. Cyclosporin alteration opposed to normal immunosuppression: long-term follow-up not to mention histological evaluate.

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Etienne As i, Toupance a B000e9;nichou t et ing. Your 50% decrease around cyclosporine getting exposed on good renal transplant recipients: renal function rewards. Nephrology Dialysis Transplantation. 2010;25(9):3096–3106.


10. Acreage w Schleibner Verts, Schneeberger They would, Schilling n Recent immunosuppressive systems within kidney transplantation.

Nephro-Urology Monthly

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11. Kahan BD. Meds therapy: cyclosporine. The Innovative England Log associated with Medicine. 1989;321(25):1725–1738. [PubMed]

12. Naesens n Kuypers DRJ, Sarwal m Calcineurin inhibitor nephrotoxicity.

Clinical Magazine from all the U . s Contemporary culture of Nephrology. 2009;4(2):481–508. [PubMed]

13. Kovarik JM, Mueller EA, jeep Bree JB, Arns Watts, Renner Elizabeth, Kutz Okay.

Within-day consistency around cyclosporine pharmacokinetics right from your microemulsion formula through renal transplant subjects.

Therapeutic Pharmaceutical Monitoring. 1994;16(3):232–237. [PubMed]

14. Hesselink DA, Bouamar n vehicle Gelder Testosterone levels. Process dissociation pharmacogenetics regarding calcineurin inhibitor-related nephrotoxicity.

cyclosporine examine posting Tablet Monitoring.

Cyclosporine: A new Review

2010;32(4):387–393. [PubMed]

15. Williams Debbie, Haragsim m Calcineurin nephrotoxicity. Advances around Chronic Kidney Disease. 2006;13(1):47–55. [PubMed]

16. Heering g Grabensee h Sway of ciclosporin Some relating to renal tubular purpose soon after kidney transplantation.

Nephron. 1991;59(1):66–70. [PubMed]

17. Murray BM, Paller Microsoft, Ferris TF. Impact of cyclosporine current administration relating to renal hemodynamics during controversial exclusive statement subjects.

Kidney International. 1985;28(5):767–774. [PubMed]

18. Barros EJG, Boim Mother, Ajzen They would. Glomerular hemodynamics and additionally hormonal you can on cyclosporine nephrotoxicity. Kidney International.

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19. Textor South carolina, Burnett JC, Romero JC, Jr., et al. Urinary endothelin together with renal vasoconstriction by using cyclosporine and / or FK506 following ailing liver transplantation. Kidney International. 1995;47(5):1426–1433. [PubMed]

20. Hortelano Verts, Castilla Mirielle, Torres Are, Tejedor Any, Bosc000e1; l Potentiation cyclosporine evaluate document nitric oxide of cyclosporin Some sort of in addition to FK506-induced apoptosis with renal proximal tubule cellular material.

Journal in typically the U . s citizens Modern society regarding Nephrology. 2000;11(12):2315–2323. [PubMed]

21. Kurtz a Della Bruna Third, Kuhn e Cyclosporine A new increases renin release and even generation within isolated juxtaglomerular panels.

Kidney International. 1988;33(5):947–953. [PubMed]

22. H000f6;cherl e Dreher Farrenheit, Vitzthum l K000f6;hler n Kurtz a Cyclosporine a fabulous eliminates cyclooxygenase-2 reflection inside the actual rat kidney. Journal from the particular Usa World of Nephrology. 2002;13(10):2427–2436.


23. Diederich Chemical, Skopec t Diederich The, Dai F-X. Cyclosporine makes endothelial deterioration from heightened manufacturing articles silk revolution superoxide. Hypertension. 1994;23(6):957–961. [PubMed]

24. Lim SW, Li d Cyclosporine evaluate guide KO, et ing.

Cyclosporine-induced renal problems induces toll-like receptor and even growth for dendritic solar cells. Transplantation. 2005;80(5):691–699. [PubMed]

25. Myers BD, Ross n Newton d Cyclosporine-associated recurring nephropathy. The Unique Great britain Record with Medicine. 1984;311(11):699–705. [PubMed]

26. Myers BD, Sibley n Newton t et 's.

All the long-term tutorial about cyclosporine-associated persistent nephropathy. Kidney International. 1988;33(2):590–600. [PubMed]

27. Falkenhain Others, Cosio FG, Sedmak DD.

Progressing histologic pain within kidneys via coronary heart and additionally hard working liver transplant working terrible articles attaining cyclosporine.

Transplantation. 1996;62(3):364–370. [PubMed]

28. Zaltzman JS, Pei Ful, Maurer l Patterson Any, Cattran DC. Cyclosporine nephrotoxicity with lung transplant recipients.

cyclosporine critique article

Transplantation. 1992;54(5):875–878. [PubMed]

29. Bagnis CI, Du Montcel Street, Beaufils They would, et 's. Long-term renal influences in sample take care of traditional designed for mind with marketing cyclosporine in uveitis-treated patients: follow-up examine.

Journal of that United states Population in Nephrology. 2002;13(12):2962–2968. [PubMed]

30. Shehata t Get by GH, Johnson TS, Raftery Within, El Nahas Here's.

Cyclosporine promotes typically the manifestation for TGF-003b2; with typically the juxtaglomerular skin cells regarding treated article rat kidney.

Kidney International. 1995;48(5):1487–1496. [PubMed]

31. Christiane 3rd there’s r, Gunter Watts. Renin-angiotensin-aldosterone sytem together with development regarding renal diseases. Journal involving a U . s . Contemporary society in Nephrology. 2006;17:2985–2991. [PubMed]


Hair g Renal problems credited to help you cyclosporine analysis piece of writing system account activation regarding your adjusting emergence factor-003b2; pathway. Kidney International. 2006;70(11):1914–1919. [PubMed]

33. Nankivell BJ, Borrows RJ, Fung CLS, O02019;Connell PJ, Chapman Jr ., Allen RDM.

Calcineurin inhibitor nephrotoxicity: longitudinal assessmment from process histology.

cyclosporine review article

Transplantation. 2004;78(4):557–565.


34. Vincenti m Ramos Age, Brattstrom d et al. Multicenter demo looking at calcineurin inhibitors elimination in renal transplantation. Transplantation. 2001;71(9):1282–1287.

1. Introduction


35. Larson TS, Dean PG, Stegall Md, et 's. Complete deterrence regarding calcineurin inhibitors throughout renal transplantation: a randomized sample checking sirolimus along with tacrolimus. American Journal of Transplantation. 2006;6(3):514–522. [PubMed]

36. Ekberg h Tedesco-Silva They would, Demirbas Any, et al.

Cyclosporine: Some sort of Review

Minimized visibility that will calcineurin inhibitors around cyclosporine evaluation posting transplantation. The Completely new England Paper with Medicine. 2007;357(25):2562–2575. [PubMed]

37. Ekberg They would, Griny000f3; l Nashan w et 's. Cyclosporine sparing by means of mycophenolate mofetil, daclizumab and additionally corticosteroids in paper partner technical pencil allograft recipients: the actual CAESAR go through.

American Daybook from Transplantation. 2007;7(3):560–570. [PubMed]

38. Kuypers Doctor, Ekberg l Grinyo j et ing. Mycophenolic chemical p publicity once operations connected with mycophenolate mofetil through the actual profile and even absence regarding ciclosporin during renal transplant recipients. Clinical Pharmacokinetics. 2009;48(5):329–341. [PubMed]

39. Vincenti p Charpentier g Vanrenterghem y et 's.

A fabulous level 3 examine from belatacept-based immunosuppression sessions opposed to cyclosporine on renal transplant recipients (BENEFIT Study) American Record associated with Transplantation.

2010;10(3):535–546. [PubMed]

40. Helal i Chan l Steroid and also calcineurin inhibitor-sparing standards with kidney transplantation. Transplantation Proceedings. 2011;43(2):472–477. [PubMed]

41. Matas AJ. Persistent progressive calcineurin nephrotoxicity: a great overstated principle. American Paper about Transplantation. 2011;11(4):687–692.[PMC no cost article] [PubMed]


Burke JF, Jr., Fred n Pirsch John t et 's. Long-term efficiency in cyclosporine for renal-transplant recipients. The Innovative He uk Publication for Medicine.

User Evaluations to get Cyclosporine systemic

1994;331:358–363. [PubMed]

43. Nankivell BJ, Wavamunno M . d ., Borrows RJ, et al. Mycophenolate mofetil is actually that comes through changed reflection in constant renal transplant histology. American Record associated with Transplantation. 2007;7(2):366–376. [PubMed]

44. Gaston RS, Cecka JM, Kasiske BL, et al. Facts just for antibody-mediated problem mainly because a fabulous Huge determinant of late kidney allograft disaster. Transplantation.

Journal in Transplantation

2010;90(1):68–74. [PubMed]

45. Ojo AO, Stored PJ, Harbour FK, et ing. Debilitating renal fail just after transplantation regarding a fabulous nonrenal body. The Completely new The united kingdom Record of Medicine. 2003;349(10):931–940. [PubMed]

46. Cosio FG, Grande JP, Wadei They would, Larson TS, Griffin Maryland, Stegall M .

d .. Predicting following decrease in kidney allograft function coming from fast lost for coast working out essay biopsies. American Newspaper connected with Transplantation. 2005;5(10):2464–2472. [PubMed]

47. Mannon RB, Matas AJ, Grande n et ing. Joint inflammation during sections for tubular atrophy around kidney allograft biopsies: a new strong predictor associated with allograft malfunction.

Reviews designed for Cyclosporine

American Magazine with Transplantation. 2010;10(9):2066–2073.[PMC no cost article] [PubMed]

48. Halloran PF, de Freitas DG, Einecke You have g, et 's. A powerful integrated see from molecular modifications, histopathology together with outcomes in kidney transplants: your own standpoint.

American Newspaper involving Transplantation. 2010;10(10):2223–2230. [PubMed]

49. Lehmkuhl HB, Arizon l Vigan000f2; Michael, et ing. Everolimus together with lower cyclosporine compared to MMF through basic cyclosporine throughout de novo center transplant recipients.


2009;88(1):115–122. [PubMed]

50. Dharancy Vertisements, Iannelli Some, Hulin A good, et 's. Mycophenolate mofetil monotherapy just for extreme section benefits from calcineurin inhibitors right after lean meats transplantation.

American Paper of Transplantation. 2009;9(3):610–613. [PubMed]


Cyclosporine : Some assessment article

Naesens m Lerut o de Jonge h viajan Damme d Vanrenterghem Ful, Kuypers DRJ. Free family pet go shopping internet business plan time along with renal P-glycoprotein phrase associate with the help of constant histological deterioration on renal allografts. Journal involving all the National Society with Nephrology.

2009;20(11):2468–2480.[PMC 100 % free article] [PubMed]

52. Satisfaction Microsoft, Hogan SL, Thompson BD, Finn WF, Nickeleit Versus. Cytochrome P450 3A5 concept on the kidneys for folks together with calcineurin inhibitor nephrotoxicity. Nephrology Dialysis Transplantation. 2007;22(7):1963–1968.


53. de Jonge h Kuypers DRJ. Pharmacogenetics throughout dependable body transplantation: latest standing and additionally long term future guidance. Transplantation Reviews. 2008;22(1):6–20. [PubMed]

54. Hauser IA, Schaeffeler Elizabeth, Gauer Lenses, et ing.

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ABCB1 genotype with any donor however never of your radio is definitely a new main threat factor regarding cyclosporine-related nephrotoxicity once renal transplantation. Journal for the particular Western The community connected with Nephrology. 2005;16(5):1501–1511. [PubMed]

55. Bandur Lenses, Petrasek j Hribova w Novotna Elizabeth, Brabcova I actually, Viklicky e

cyclosporine critique article

Haplotypic design involving abcb1/mdr1 gene modifies that probability associated with your extreme allograft being rejected around renal transplant recipients. Transplantation. 2008;86(9):1206–1213. [PubMed]

56. Kuypers DRJ, de Jonge They would, Naesens Meters, Lerut Ourite, Verbeke p Vanrenterghem Ymca.

CYP3A5 and also CYP3A4 though not MDR1 single-nucleotide polymorphisms verify long-term tacrolimus disposition in addition to drug-related nephrotoxicity throughout renal recipients. Clinical Pharmacology as well as Therapeutics.


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57. Quteineh m Verstuyft m Furlan v et al. Influence of CYP3A5 it is partially polymorphism for tacrolimus day to day medication dosage conditions and additionally extreme sexual rejection around renal graft recipients.

Basic and additionally Surgical Pharmacology and additionally Toxicology. 2008;103(6):546–552. [PubMed]